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The graphs below show the prevalence of prescription drug use disorder by age of first nonmedical use of prescription drugs. Among those who first used a prescription drug nonmedically at age 13, about 42% experienced prescription drug abuse, and 25% experienced prescription drug dependence in their lifetime. Note: Before the DSM-V, substance use disorder was divided into classes termed “abuse” and “dependence.” Today substance use disorder is classified as mild, moderate, and severe.

Each year that children and young adults delay their first use of any substance, the less likely they will be to develop a substance use disorder later.